Caution is needed in interpreting HIV transmission chains by ultradeep sequencing

Caution is Needed in Designing Pharmacy Coverage

P harmaceuticals are a critical component of modern medical care and have contributed substantially to health and quality of life. They are also expensive, accounting for 10% of US health care costs. By the end of this year, Medicare beneficiaries are expected to spend $343 billion on medications, and drug spending is projected to grow faster than both the inpatient and outpatient care categori...

Quantum Calculations Show Caution Is Needed In Interpreting Methanethiosulfonate Accessibility Experiments On Ion Channels

Standard models of ion channel voltage gating require substantial movement of one transmembrane segment, S4, of the voltage sensing domain. Evidence comes from the accessibility to external methanethiosulfonate (MTS) reagents of the positively charged arginine residues (R) on this segment. These are first mutated to cysteines (C), which in turn react with MTS reagents; it is assumed that the C ...

Going Solar is Good but Caution Needed!

Why not treat the mother-infant dyad, rather than infant alone, as achieving vitamin D sufficiency is equally important for the mothers. Compliance with daily oral vitamin D supplementation of infants is documented to be very poor even in the West [4,5]. Exposing infants to sunlight may be a more difficult proposition than medicinal supplements. While the natural way of augmenting the vitamin D...

Operational models of allosteric modulation: caution is needed.

Lymphocyte dynamics: caution in interpreting BAL numbers.

In various allergic and inflammatory lung diseases the number and subset composition of lymphocytes in the bronchoalveolar lavage (BAL) fluid are taken as indicators of the state of the disease. The number of lymphocytes in the BAL fluid depends on three main parameters: (1) entry into the bronchoalveolar space from the different compartments of the lung, (2) persistence in the bronchoalveolar ...